Single nucleotide polymorphism array analysis of bone marrow failure patients reveals characteristic patterns of genetic changes
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چکیده
منابع مشابه
Single Nucleotide Polymorphism Analysis of Protamine Genes in Infertile Men
Background Single nucleotide polymorphism (SNPs) are considered as one of the underlying causes of male infertility. Proper sperm chromatin packaging which involves replacement of histones with protamines has profound effect on male fertility. Over 20 SNPs have been reported for the protamine 1 and 2. MaterialsAndMethods The aim of this study was to evaluate the frequency of two previously repo...
متن کاملHigh-resolution single nucleotide polymorphism array analysis of epithelial ovarian cancer reveals numerous microdeletions and amplifications.
PURPOSE Genetic changes in sporadic ovarian cancer are relatively poorly characterized compared with other tumor types. We have evaluated the use of high-resolution whole genome arrays for the genetic profiling of epithelial ovarian cancer. EXPERIMENTAL DESIGN We have evaluated 31 primary ovarian cancers and matched normal DNA for loss of heterozygosity and copy number alterations using 500 K...
متن کاملan infinite planar array of rectangular microstrip patch antenna analysis
the methods which are used to analyze microstrip antennas, are divited into three categories: empirical methods, semi-empirical methods and full-wave analysis. empirical and semi-empirical methods are generally based on some fundamental simplifying assumptions about quality of surface current distribution and substrate thickness. thses simplificatioms cause low accuracy in field evaluation. ful...
15 صفحه اولsingle nucleotide polymorphism analysis of protamine genes in infertile men
background: single nucleotide polymorphism (snps) are considered as one of the underlying causes of male infertility. proper sperm chromatin packaging which involves replacement of histones with protamines has profound effect on male fertility. over 20 snps have been reported for the protamine 1 and 2. materials and methods: the aim of this study was to evaluate the frequency of two previously ...
متن کاملApplication of single-nucleotide polymorphism (SNP) as a molecular marker in the study of genetic diversity of aquatic populations
Genetic diversity is one of the important and essential characteristics of any population for its survival. The study of genetic variation in different populations of aquatic organisms is of particular importance in order to protect, stabilize and manage their stocks. Based on studies conducted in recent years, molecular markers have proven that they can be used as indicators of the genetic div...
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ژورنال
عنوان ژورنال: British Journal of Haematology
سال: 2013
ISSN: 0007-1048
DOI: 10.1111/bjh.12603